Downstream approaches to atrial fibrillation: the new rhythm control drugs and promising targets.
نویسندگان
چکیده
منابع مشابه
New pharmacological approaches to atrial fibrillation.
Atrial fibrillation (AF) is the most common cardiac arrhythmia facing physicians, afflicting 13% of men and 11% of women over 85 years of age. Epidemiological studies estimate that there are ≥ 11 million AF sufferers in the seven major economies and that its prevalence will increase two- to threefold over the next 50 years. Current strategies for treating AF involve either sinus rhythm (SR) mai...
متن کاملRate versus rhythm control in atrial fibrillation.
OBJECTIVE To determine whether rate control is a viable initial treatment approach in persistent atrial fibrillation (AF) through the evaluation of recently completed trials comparing rate and rhythm control. DATA SOURCES Biomedical literature was obtained through MEDLINE (1966-December 2003) and the Iowa database. STUDY SELECTION AND DATA EXTRACTION Articles identified from the biomedical ...
متن کاملAblation to treat atrial fibrillation: beyond rhythm control.
Pathogenesis Until the mid to late 1980s, the “multiple wavelet hypothesis,” developed by Moe, was the most widely accepted theory of the mechanism of atrial fibrillation. The arrhythmia was described as a large number of propagating wave fronts with variable refractory and conduction properties leading to the development of multiple reentrant circuits. However, to maintain atrial fibrillation,...
متن کاملIs rate control or rhythm control preferable in patients with atrial fibrillation? Rate control is preferable to rhythm control in the majority of patients with atrial fibrillation.
An Argument for Maintenance of Sinus Rhythm in Patients With Atrial Fibrillation Print ISSN: 0009-7322. Online ISSN: 1524-4539 Copyright © 2005 American Heart Association, Inc. All rights reserved. is published by the American Heart Association, 7272 Greenville Avenue, Dallas, TX 75231 Circulation doi: 10.1161/CIRCULATIONAHA.104.537175 2005;111:3150-3156 Circulation. http://circ.ahajournals.org...
متن کاملThe AFFIRM study: approaches to control rate in atrial fibrillation.
1. Olshansky B, Rosenfeld LE, Warner AL, et al., for the AFFIRM investigators. The Atrial Fibrillation Follow-up Investigation of Rhythm Management (AFFIRM) study: approaches to control rate in atrial fibrillation. J Am Coll Cardiol 2004;43:1201–8. 2. Wyse DG, Waldo AL, DiMarco JP, et al. A comparison of rate control and rhythm control in patients with atrial fibrillation. N Engl J Med 2002;347...
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ژورنال
عنوان ژورنال: Folia Pharmacologica Japonica
سال: 2010
ISSN: 0015-5691,1347-8397
DOI: 10.1254/fpj.135.62